Just to tell you this solution (setting the target processor to "any cpu") also worked for me.
Here is how to do:
-Display your Silverlight application project's properties.
-Under the 'compiling' tab, set the 'target CPU' to 'Any CPU'. Remark: maybe due to a display bug, I first could not access that option, because it was not visible in the displayed part of the window, and no vertical scrollbar was present. I had to enlarge the project properties window high enough to be able to see it.
My symptoms were:
Chrome displayed a blank page, but no error message (maybe it was simply not configured to, but then it is because the default settings of this browser don't show these errors)
Unhandled Error in Silverlight Application
Message: Failed to load pre-requisites for the application
Hopes this helps someone in the future